We all know about the entourage effect and if you don’t you can find it here!
Recent studies have shown that CBD actually blocks THC binding to the CB1 receptor in the endocannabinoid system. Our endocannabinoid system is located in the body’s central and peripheral nervous systems, including cannabinoid receptors CB1 and CB2.
CBD doesn’t bind directly to either cannabinoid receptor. Instead, it acts against cannabinoid agonists. CBD also interacts with various other receptors throughout the body.
Both CBD and THC have the exact same molecular structure, however a small difference in how the atoms are arranged is what causes the mind-altering effects of THC. Interaction with your endocannabinoid system mimics your body’s own endocannabinoids. These interactions release neurotransmitters in your brain. Neurotransmitters are chemicals responsible for relaying messages between cells and have roles in pain, immune function, stress, sleep, to name a few.
This is why CBD works so well to alleviate pain, improve mental health issues such as anxiety and depression and also help conditions such as seizures and epilepsy.
Because we have discovered that CBDs block THC from attaching to the receptors, thus blocking the mind-altering effects, it’s less effective to take the two together if one is looking for the “high”. THC free products are also beneficial for those looking for the healing benefits of CBD but are subject to drug tests.
So while you can in fact experience the benefits of the entourage effect, depending on your situation it might be more beneficial to take them individually at different times a day or use a THC free CBD product.
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